Answer:
My first is in some but not in all. My second is into but not in tall. My third in little but no in big. My fourth in port but not in pig. My whole is made in nature's way. For clothing, rugs used every day.
What do you purposefully put lots of in and on your body, but run away from when you encounter it outside?
It can cause deflation of tires when dropped from the rear of spy cars.
What is often returned, but never borrowed/
They have not flesh, nor feathers, nor scales, nor bone. Yet they have fingers and thumbs of their own.
What did the piece of wood say when he saw the screwdriver and screws approaching?